COUNTERACTING misinformation about immunisation is the responsibility of everyone, from medical journals to social media executives, health professionals and the general public, say experts.

Associate Professor Helen Petousis-Harris, a vaccinologist from the University of Auckland, told InSight+ that vaccine opponents had been around since Edward Jenner inoculated 8-year-old James Phipps with cowpox on 14 May 1796.

“And they used very much the same arguments as we see today – the idea that there’s toxic ingredients in vaccines; there’s the Big Pharma and government conspiracy stuff; the idea that there’s a lack of vaccine effectiveness, and the whole back to nature idea,” she told InSight+.

“When you look at them you can see that they play to the core of quite a variety of beliefs or philosophies like chemophobia, transpirational beliefs, and things like that.”

Associate Professor Petousis-Harris and her colleague Lisbeth Alley have written a Perspective published in the MJA.

The internet, and particularly the rise of social media since 2000, has “changed the paradigm” for anti-vaccination campaigns.

“Now you can not only access everything instantly, you can send things anywhere instantly,” Associate Professor Petousis-Harris said.

“We started with people having websites and also email – that’s where it started and that allowed interest groups to easily collaborate. Key actors, no matter where they were in the world could start getting together.

“That’s allowed the [antivaccination] movement to get more organised, but also to start getting financed. The internet allows key actors to receive considerable revenue.

“And then along came Facebook … those algorithms started to improve the targeting of messages, so people get messages that they’re most receptive to. We all know about the echo chambers, and the research has shown that lies spread faster, further, and deeper than the truth.

“Research also shows that people who haven’t made up their minds are more likely to be recruited over to what I guess you consider the core antivaccine pages.”

If and when a COVID-19 vaccination comes along, Associate Professor Petousis-Harris has concerns about how it will be received.

“We’ve got quite a critical situation where we have polarisation happening, as opposed to social cohesion,” she said.

“I think the vaccine thing is just part of the bigger picture. At the moment we seem to be seeing a perfect storm of people opposed to 5G, people who oppose vaccines, and people arguing about civil liberties – all coming together. This is the growing perfect storm.”

Combatting antivaccination arguments is complex, and the responsibility of all in health care, Petousis-Harris and Alley wrote.

“Research consistently finds that people who have a warm trusting relationship with a confident and knowledgeable health provider are more likely to vaccinate themselves and their children,” they wrote.

“It is vital that vaccinators keep up to date with current memes and themes and are able to respond confidently and effectively to the questions that arise.

“When education and resources for these professionals are not accessible and funded, then working with vaccine-hesitant people is challenging and stressful. Providers could use social media and their own websites to craft and promote positive immunisation messages for their community. Posting messages that support patient and parental confidence in the safety and effectiveness of vaccines, and raising awareness that most infants are fully immunised, helps embed immunisation as normal health behaviour.

“Evidence also supports the use of personal stories and anecdotes that resonate with vaccine-hesitant parents; infographics can help bypass anecdotes.”

Petousis-Harris and Alley concluded that although the issue was a complex one, maintaining trust in health care was key.

“There is no one-size-fits-all in this space; solutions at times appear uncertain. Recognising the complexity of this problem is the first step, and maintaining trust in health professionals, health ministries, government, global and professional health bodies and scientists is essential.”

Meanwhile, new data on the vaccination front are encouraging for those supporting the national “no jab, no pay” policy.

Another study published in the MJA, shows that “no jab, no pay” was associated with substantial catch-up vaccination activity in lower socio-economic status areas in the 2 years after it was implemented.

Introduced on 1 January 2016, “no jab, no pay” extended the existing vaccination requirements for receiving federal family assistance payments by removing non-medical (conscientious objection) exemptions and tightening guidelines for medical exemptions.

Researchers from the National Centre for Immunisation Research and Surveillance (NCIRS) and the University of Sydney analysed data from the Australian Immunisation Register for catch-up vaccination of children aged 5 to less than 7 years before (January 2013 – December 2014; baseline) and during the first 2 years of “no jab, no pay” (December 2015 – December 2017), and of children aged 7 to less than 10 years and young people aged 10 to less than 20 years (“no jab, no pay” period only).

They also examined catch-up vaccination rates for the second dose of measles–mumps–rubella vaccine (MMR2) in the latter two age groups, by Indigenous status and socio-economic status, and for the third dose of diphtheria–tetanus–pertussis vaccine (DTPa3) and MMR1 in children aged 5 to less than 7 years, before and after the introduction of “no jab, no pay”.

“The proportion of incompletely vaccinated children aged 5 to less than 7 years who received catch-up DTPa3 was higher under “no jab, no pay” than during the baseline period (15.5% v 9.4%),” the authors found. However, they also found a slight reduction in MMR1 catch-up (13.6% v 12.9%).

“Of 407 332 incompletely vaccinated adolescents aged 10 to less than 20 years, 71 502 (17.6%) received catch-up MMR2 during the first 2 years of “no jab, no pay”. This increased overall coverage for this age group from 86.6% to 89.0%.

MMR2 catch-up activity in this age group was greater in the lowest socio-economic status areas than in the highest socio-economic status areas (29.1% v 7.6%), and also for Indigenous than for non-Indigenous Australians (35.8% v 17.1%).

“Our findings suggest that, while monetary sanctions are effective in promoting catch-up vaccination, their impact varies with socio-economic disadvantage,” concluded the authors, led by Dr Frank Beard, NCIRS Associate Director, Surveillance, Coverage, Evaluation and Social Science, and Senior Lecturer, University of Sydney.

“Moreover, the lack of change in MMR1 catch-up activity in children aged 5 to less than 7 years suggests little impact on those who reject vaccination, and that expansion of age requirements was the more effective policy lever in this period,” he added.

Professor Julie Leask, NCIRS Professorial Fellow and University of Sydney expert on vaccination attitudes and behaviour commented, “Many factors contribute to incomplete vaccination; a comprehensive suite of measures, particularly for reducing barriers to access and incorporating systematic reminders, is therefore essential for improving coverage. Requirements alone are not enough.

“The full scope of consequences of strict vaccination requirements should be carefully examined by any country considering such measures. It may be possible to find a reasonable middle ground that increases catch-up while not disadvantaging certain families.”


"No jab, no pay" has proven its worth
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7 thoughts on “Vaccination hesitancy: trust in health professions key

  1. Sue Ieraci says:

    Links to articles that are posted without comment are seldom helpful in discussion. IN particular, links to discredited work such as Exley’s is prolematic (explained here:>

    Aluminium is one of the earth’s most abundant elements. We absorb it from foods and drink all the time – babies absorb it from breast milk. It circulates to the kidneys and gets excreted. ANyone looking for a reliable reference to reassure their patients might find this useful, from the CHildrens Hospital of Philadelphia:

  2. ROGER BURGESS says:

    Any, repeat ANY, stratagem that directly or indirectly leads to effective herd immunity is fair game…achtung!

  3. Bryan Cebuliak says:

    Masson JD, Crépeaux G, Authier FJ, Exley C, Gherardi RK. Critical analysis of reference studies on the toxicokinetics of aluminum-based adjuvants. J Inorg Biochem. 2018 Apr;181:87-95. doi: 10.1016/j.jinorgbio.2017.12.015. Epub 2017 Dec 28. PMID: 29307441.

  4. Sue Ieraci says:

    In response to “Max”, it must be understood that very few people promote “forced” vaccination – though many of us understand and support the use of incentives and disincentives for people to comply with the conventions to contribute to the wellbeing of our civil society.

    “No jab no pay” has been one such successful strategy. The Family Tax Benefit part that is contingent on showing up-to-date vaccination incorporates the previous “Maternity Immunisation Allowance” – which was a targeted incentive payment. Those who don’t comply with the requirements don’t get the financial benefit.

    There is good evidence that a large number of children completed vaccination as a result of this measure.

  5. Bryan Cebuliak says:

    Exley C. An aluminium adjuvant in a vaccine is an acute exposure to aluminium. J Trace Elem Med Biol. 2020 Jan;57:57-59. doi: 10.1016/j.jtemb.2019.09.010. Epub 2019 Sep 18. PMID: 31561170.

  6. Max says:

    It has become fashionable to scoff at civil liberty arguments against vaccination, and more topically lockdown strategies.
    Nevertheless, doctrinaire physicians would do well to re-acquaint themselves with the philosophical underpinnings upon which our society is based.
    You may say ‘ I know what’s best for you’, however there are still several steps between that and ‘you must do as I say’.
    Financial coercion to be vaccinated might be thought valid given non – vaccinators are freeloading on the herd immunity of the rest of us, but it is unsurprising that those with a philosophical objection rather than just an absence of mind were not swayed.
    We are required as physicians to respect religious and other deeply held personal views.
    Forced or mandatory vaccination is and should remain a physical assault on autonomy and personal liberty.

  7. Marcus F. Rumpus says:

    Good commentary.

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