EXPERTS are divided on how doctors should manage patients with central obesity.

Professor Susan Davis, endocrinologist and Director of the Specialist Women’s Health Clinic at Alfred Health, was commenting on new research published in JAMA Open which found that postmenopausal women with normal body mass index (BMI) and central obesity – characterised by relatively high abdominal fat distribution – were at higher risk of cardiovascular disease mortality and cancer mortality than those with normal BMI without central obesity.

“There’s not much that’s that new in this particular study, but it reinforces what others have shown in smaller studies … at a population scale,” Professor Davis told InSight+.

The study was a prospective cohort study of 156 624 postmenopausal women enrolled in the Women’s Health Initiative at 40 clinical centres in the US between 1993 and 1998.

During the study period 43 838 deaths occurred, including 12 965 deaths from cardiovascular disease (29.6%) and 11 828 deaths from cancer (27.0%), the JAMA Open authors found.

“Compared with women with normal weight and no central obesity and adjusted for demographic characteristics, socio-economic status, lifestyle factors, and hormone use, the hazard ratio for all-cause mortality was 1.31 (95% CI, 1.20–1.42) among women with normal weight and central obesity, 0.91 (95% CI, 0.89–0.94) among women with overweight and no central obesity, 1.16 (95% CI, 1.13–1.20) for women with overweight and central obesity, 0.93 (95% CI, 0.89–0.94) for women with obesity and no central obesity, and 1.30 (95% CI, 1.27–1.34) for women with obesity and central obesity,” the study authors reported.

“Compared with normal weight without central obesity, normal weight central obesity was associated with higher risk of cardiovascular disease mortality (hazard ratio, 1.25; 95% CI, 1.05–1.46) and cancer mortality (hazard ratio, 1.20; 95% CI, 1.01–1.43).”

Professor Davis said Australians as a society had become “complacent” about overweight and obesity.

“We have just published a study of 6600 women aged 18 to 39 years, recruited from Victoria, Queensland and New South Wales – 46% of them are overweight or obese. They haven’t even hit their forties or menopause,” she said.

“We’re not coming down on this heavily enough in the guidelines – any central abdominal obesity, irrespective of your BMI, is problematic.

“It’s okay to tell your patients ‘you need to lose weight’ even if they’re just a bit overweight or even if they’re normal BMI but they’re carrying it centrally.”

Professor John Dixon, from the Baker Heart and Diabetes Institute, said the situation was more complicated.

“The problem is, how do we change where we distribute our weight,” he told InSight+.

“[In a postmenopausal woman] who is normal weight, we can’t advise them to lose weight if they are normal weight already.

“For an obese patient, we’d say if you have a 5% weight loss it’s going to be very helpful for you,” Professor Dixon said.

“[But if we said that to] someone who’s normal weight, we’re putting muscle at risk and we’re putting bone at risk.

“And in fact, when you’re postmenopausal, when you’re in your 60s and 70s, a little bit overweight is actually associated with a longer life.”

Professor Dixon said the key to reducing cardiometabolic risk in people with normal weight and central obesity was not weight loss, but modifying cardiovascular risk factors.

“We need to check that they haven’t got diabetes. We need to keep an eye on the blood pressure and the lipids, and we need to make sure that the diet is healthy and there is plenty of exercise,” he said.

“The most important thing for healthy ageing is a healthy exercise program – aerobic activities, resistance activities, balanced active core activities.

“We don’t need them to lose weight. We need them to eat well, be very fit, and to look after their cardiometabolic risk factors.”

6 thoughts on “Central obesity: postmenopausal weight management

  1. Rachel says:

    We need to educate people about insulin resistance and lowering carbohydrate intake. Why aren’t more patients tested for fasting insulin levels? All of these factors contribute to pre and post menopausal women carrying extra weight around their central trunk, even if their weight is normal.

  2. Anonymous says:

    Yes……exercise !….lose weight !…..eat less and BURN the excess and ‘stored’ calories and fat ; not so complicated,
    just simple arithmetic !!

  3. Elijah says:

    Reduce Carbs to the minimum
    Practice meditation/relaxation
    Regular physical activity
    Late breakfast/brunch and early light dinner
    Small meals
    Eat slowly
    High water intake
    Red wine good, no beer

  4. Dr Andrew Wettenhall says:

    Things wont change until hyperinsulinaemia’s driving role in insulin resistance is accepted and dietary advice is corrected for those on the metabolic syndrome slide. Easy to prevent – harder to fix once the vicious cycle has set in

  5. Anne M Taylor says:

    OK Anonymous, tell them that — but it’s useless to do so unless you provide detailed methods of achieving your goal. What kind of exercise, how much and how do they design their eating to achieve the lowered calorie count? What if your patient has arthritis and has been told no to stress their joints, what if they are vegetarian, how do they replace fats in the diet. It IS complicated to the patient.

  6. C.K. says:

    Is it easy to lose weight, increase exercise & change the average diet? No, it most definitely is NOT!!!

    I find it incredulous that some very common (albeit rarely or correctly diagnosed) post-menopausal diseases have not been mentioned…

    For example: I’m post menopausal, diabetic for over 12 years (after suffering undiagnosed gestational diabetes), suffer horribly with chronic neuropathy, kidney stones, have hashimoto’s, adrenal fatigue and constant high levels of stress (from caring for a child with multiple disabilities). I’m anaemic, low in D3, K2, B12 and have gut absorption issues (most likely from the copious amount of daily meds).

    So according to the ideology above, my question is this…
    How do I (and many women in similar situations) exercise (with neuropathy), stay positive (yeah right!!!), eat a healthy diet (diabetic, hashimoto’s and reduce kidney stones), and lose central fat? Bare in mind Hashimoto’s also causes a layer of dark brown fat called MUCIN to be deposited all over the body and once there, cannot be removed by dieting.

    Anyone game to respond?

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