WOMEN who report experiencing “baby brain” during pregnancy can be assured that it’s not all in their head, with Australian researchers confirming in the MJA that a small degree of cognitive impairment is associated with pregnancy.

A meta-analysis of 20 studies including 709 pregnant women and 521 non-pregnant women, found that overall cognitive functioning was poorer in pregnant than in non-pregnant women (standardised mean difference [SMD], 0.52; 95% CI, 0.07–0.97; P = 0.025).

An analysis of cross-sectional studies showed that general cognitive functioning, memory and executive functioning were all significantly reduced during the third trimester of pregnancy, but not in the first two. When looking at the longitudinal studies, the researchers found declines between the first and second trimesters in general cognitive functioning and memory, but not between the second and third trimesters.

The researchers defined general cognitive functioning broadly, including memory, attention, executive functioning, processing speed, and verbal and visuospatial abilities.

They warned that their results should be interpreted with caution, given that the cognitive function of pregnant women remained within the normal range.

“Given the small to moderate effect sizes of the differences and the limited number of longitudinal studies available, our findings need to be interpreted with caution, particularly as the declines were statistically significant, but performance remained within normal ranges of general cognitive functioning and memory,” they wrote.

Lead author Sasha Davies, a PhD candidate at Deakin University, said that the degree of cognitive impairment found in the study was not extreme and usually only noticeable to the woman herself, and perhaps her partner.

“So as much as you might see a small cognitive decline, it’s not going to be anything that is very drastic,” Ms Davies told MJA InSight. “We don’t think it’s going to affect their professional lives or their personal lives.”

Ms Davies said that researchers were yet to identify the mechanisms responsible for the change. She said factors such as hormone levels, stress, anxiety and mood changes had been suggested in other studies.

“We know that all those factors have an impact on cognition in other groups, but we don’t know that that’s the key reason for this change that we see in pregnancy,” Ms Davies said.

She added that there were also suggestions in the literature that cognitive declines in areas such as executive functioning and memory may be offset by improved cognitive functioning in other areas.

An intriguing study published last year showed there are reductions in grey matter in the brains of pregnant women in regions known to be closely tied to processing social information, such as decoding infant facial expressions and establishing healthy bonding between mum and baby. This presents a compelling idea that ‘baby brain’ is actually an important adaptive phenomenon that might help women prepare for raising their children by allowing their brains to adapt to their new role as new mothers,” Ms Davies said.

In an MJA InSight podcast, co-author Associate Professor Linda Byrne, Deputy Head of the School of Psychology at Deakin University, said that there were several steps that women could take to minimise the impact of these cognitive changes in pregnancy.

“Fatigue often plays a big part in our cognitive functioning, so sleep hygiene is really important … particularly in the first and last trimesters. In the first trimester when you have the massive surge of hormones and you’re feeling unwell, and in the last trimester when you’re large and uncomfortable, those are the two periods when people tend to report more fatigue. So, making sure that you’re well rested, that’s going to improve your cognitive abilities,” she said.

Maintaining good nutrition and exercise habits were also important, Professor Byrne said. She also advised women to make use of memory aids, such as phone apps and reminders.

“Even for people who once relied upon their memory quite easily, making lists and writing reminders is a good way of just making sure that if there are important things, then we are not going to miss those.”

Mrs Davies and her research team are recruiting participants for a follow-up study that will track women from pre-pregnancy through to the post-partum years to evaluate the longer term cognitive effects of pregnancy.


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7 thoughts on ““Baby brain”: it’s a thing

  1. Stephen Page says:

    If the leader of a country should become pregnant while in office what advice may be recommended to ensure that the established history of skillful decision making remains unaffected?

  2. Steve Flecknoe-Brown says:

    Are you sure that ‘baby brain’ is not due to iron deficiency?
    Iron deficiency, even without anaemia, can cause all the symptoms described above. The brain relies exclusively on glucose, metabolised aerobically, for its energy supply. Iron deficiency can deplete intracellular cytochrome oxidase enzymes, slowing aerobic glycolysis and thus producing short attention span and emotional lability. It also reduces exercise capacity, interfering with natural sleep patterns.
    Other nations include iron studies in the routine antenatal screen. We do not. We should.
    The Royal College of Pathologists of Australasia considers that a ferritin level of less than 30 microgram per litre is diagnostic of iron deficiency: male or female, pregnant or not.

  3. Jules Black says:

    Mea culpa. May I respectfully point out that book was published 30 years ago now? Whereas I cannot argue with perceptions, I for one have moved on from there decades ago.

  4. Anonymous says:

    To Jules Black … ewwwwwwwwwwwwwwwww … your artful choice of words — “deliciously”? Really? — suggests you find a woman more attractive when she’s less intelligent … #Time’sUp Jules … back to the man-cave with you

  5. Jules Black says:

    Plus ça change. Here is an extract from my bestselling book “Bodytalk: An A-Z Guide to Women’s Health”, 1988, Angus & Robertson.
    “One of the most delightful transformations in pregnancy is the vagueness which a lot of women develop. Many women have university degrees at home which attest to their superior intelligence: doctors, lawyers, PhDs, psychologists, schoolteachers and scientists. Yet when they advance through their pregnancies, their intelligence circuitry seems to crash and they become deliciously vague. Appointments are forgotten, they turn up on the wrong days and so forth, things they would never do under more normal circumstances. Fortunately, this temporary loss of intelligence disappears a few weeks or months after the birth!”

  6. sociologist says:

    Long term studies will be illuminating- also the effect of life style changes – postpartum sleep deprivation or sleep pattern alteration – is there further alteration of cerebral activity ? how permanent are the alterations and change of behavioural direction?

  7. Vesna says:

    Fantastic example of a conversation piece that has been simplistically reported by the broader media feeding into stereotypes that pregnant women are forgetful and are of no use-it’s very oppressive. Thank you Deakin Uni, nice impact. I thought that the Time was Up?

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