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THE year 1996 was a great one for colorectal cancer screening. Fifteen years later we seem to be teetering on a precipice of fiscal indecision as we wait for the outcome of the 2011 federal budget that could make or break the National Bowel Cancer Screening Program.
It was in 1996 that the first Australian cost-effectiveness evaluation of colorectal cancer (CRC) screening was reported, using outcomes from the US randomised controlled trial that compared screening with no screening (reported in 1993) and Australian health care cost data.
Just months earlier, the results of the population-based controlled trials of guaiac-based faecal occult blood tests (gFOBT) undertaken in Denmark and the UK were published, making it “3 out of 3” in terms of Level I evidence supporting the value of CRC screening.
This boded well for implementation of a national screening program in Australia, destined to be the first and only organised screening program for cancer to be made available to men as well as women.
A long and thorough process of negotiations with government and health departments eventually led to the national roll-out of the National Bowel Cancer Screening Program (NBCSP), starting with a pilot involving almost 70 000 people followed by phases 1 and 2. The outcome was that over several years, people turning 55 or 65 years and latterly 50 have been offered the new and improved faecal immunochemical test.
Acceptability was proven, with 40%‒50% of people being willing to complete the test; it was also concluded that the program was feasible. Such a high acceptance rate with a first-round offer, despite almost no publicity and no public advocacy like we see in the case of breast cancer screening, was extraordinary, and proves that the Australian public is ready for this form of screening.
So we have evidence of benefit, acceptability and feasibility. What more do we need?
Modelling the costs and potential benefits of a new treatment has become the standard by which we judge whether it should be adopted, as with new drugs where Therapeutic Goods Administration listing followed by addition to the Pharmaceutical Benefits Scheme requires that cost-effectiveness be demonstrated.
Since 1996, five additional cost-effectiveness studies have explored the value of CRC screening as an objective means of determining whether it is a health priority for Australia, as outlined in an article by Pignone and colleagues in the MJA. All the studies support the conclusion reached in the 1996 study — CRC screening is cost-effective and comparable to the value of existing national programs for breast cancer and cervical cancer screening.
Pignone et al conservatively estimated that full implementation of biennial screening for people aged 50–74 years would have gross costs of $150 million; would reduce CRC mortality by 15%–25%; would prevent 300–500 deaths from CRC annually; and would save 3600–6000 life-years annually. This would be achieved at a cost per life-year-gained of $25 000–$41 667. This is at the inexpensive end of all medical treatments.
So, to benefit, acceptability and feasibility we can add proven cost-benefit.
Can we do better and achieve a cost saving, as calculations in the Netherlands suggest that over 2‒3 decades of CRC screening will actually save money? CRC screening also prevents cancer in addition to increasing the chance of early diagnosis.
This is almost achievable, as Pignone et al calculated conservatively that in the shorter term, our NBCSP, if fully rolled out, would achieve the above benefits at a net cost to Australia’s health care system of just $50 million approximately (gross annual costs of $150 million offset by $50-100 million in savings).
So, to proven benefit, acceptability, feasibility and cost-benefit, we add affordability.
Why then do we have an unfunded and only partly rolled out NBCSP, with none of the rescreening known to be essential from the evidence and no screening above age 65, also supported by the evidence?
How can we justify failure to sustain the only nationally organised screening program that includes men as well as women, particularly when two similar programs for women (breast and cervix) have been available for years?
Even fiscal uncertainty fails to be a sustainable reason given the thorough modelling that has been presented.
The evidence supporting the case for CRC screening in Australia is so compelling that if the NBCSP does not proceed, the very principles underlying how we decide to implement changes in health policy ― evidence of benefit, cost-effectiveness and feasibility — would seem to be mocked.
Professor Graeme Young is co-director of the Flinders University Centre for Cancer Prevention and Control, Adelaide, South Australia.
Posted 21 March 2011
There might be some money available soon.
Yet another study that casts doubt on the value of breast screening. A research team have concluded that the fall in the death rate from breast cancer is about better treatments, not screening. In the UK a number of senior doctors have called for the screening program to be scrapped and are planning on taking legal action against the NHS for failing to properly inform women of risks and benefits.
Interesting… not much is being said here, but it’s a red hot issue in the UK.
I know Breast Screen (Aust) are trying to reach a 70% target for women in the target group.
http://www.guardian.co.uk/commentisfree/2011/aug/02/breast-cancer-screen…
http://www.bmj.com/content/343/bmj.d4411
Perhaps this money will find its way to the bowel screening program, better start lobbying!
It seems that the cancer that can find the most powerful backing gets the money. It’s not how many lives are saved or if the screening actually helps anyone. Breast screening has a problem with over-diagnosis and so does prostate screening, cervical cancer is rare and the test leads to “massive” over-treatment. That last bit was stated by Dr Alex Barrett in the ABC Radio National series, “The Health Report” with Norman Swan. You can find it on the net.
We have to be very careful when we spend millions on screening because it’s hard to take the funding away. I don’t think we should use tests that are unproven without randomized controlled trials and we should not screen for rare cancer unless the test is rock solid, no point over-treating the masses looking for the rare case.
I think we waste lots of money on screening, the benefits have been overstated and money would be better spent elsewhere, but those who profit from the programs will protect their turf. I know excess biopsies make big money for doctors and Dr Gilbert Welch said that screening always increases profits as it often turns healthy people into patients with unnecessary biopsies and treatments.
Bowel screening seems to be one type of screening that might be worth the money and wouldn’t you know it, it struggles for funding.
It makes no sense to me.
Sadly it appears for governments with short-term goals bowel health is not about what’s best but about what it costs and it appears that bowels are expendable organs. I am very sad to see this as a gastroenterologist.
Unfortunately, bowel cancer remains an orphan cancer with no celebrity face to champion it. At a community level the population has either been silent or their voices denied or not listened to. Yet community acceptance of FOBT screening is obvious as is the benefit of screening. When are we going to have politicians, celebrities and physicians talking publicly about their own bowel cancer screening. Most colonoscopies are performed in the private sector, so it will largely be asymptomatic ‘public patients’ who will mostly miss out on screening or investigation for bowel cancer. Further, failure of government to provide long term funding to maintain and expand the FOBT screening will be a further blow for MEN’S HEALTH as bowel cancer predominantly affects males and males are just getting used to participation in health screening programs. FOBT is simple and easy to talk about with patients. Does the government really believe that shit is a dirty word or do they just consider FOBT to be about expensive shit?
Federal transfer payments, such as Age Pensions, Medicare and other Schedule Benefits are continuously appropriated under Special Appropriations, thus ensuring payment in response to demand levels, as opposed to the “capping” effect of payments made under annual appropriations which are, of course, subject to the vagaries of the annual budget process.
Screening programs, such as breast, cervical and even prostate, which has still to meet expectations of the research community for sufficient first level evidence, are funded via special appropriations.
So the question is, why are FOBTs not funded under special appropriations?
Dennis Bentley
Foundation Director
National Cervical Screening Program
1991-95
It would be a day of great joy when our government would make decisions based on (or even just reconcilable with) available evidence – and a day of ecstasy if such decisions would be made with any benefits in mind that would materialise later than a single election cycle.
Evidence-based government – now that would be something! Maybe my grandchildren will experience it one day in the very distant future….